Plain-English translation of NCT06444919 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing capsaicin, a compound derived from chili peppers, delivered through a skin patch to treat pain from osteoarthritis in the fingers. The study compares a stronger dose of the medication to a weaker dose to see which works better for people whose finger pain includes a nerve-related component. You'll wear the patch for 30 minutes and then be tracked over 4 months to see how much your pain improves.
Many people with finger arthritis don't get enough relief from standard pain medications like ibuprofen or acetaminophen, and some can't take them at all due to side effects or other health issues. This trial is exploring whether this medication, which works by affecting pain signals in the skin and nerves, might be a helpful option for people in that situation.
You likely qualify if…
You likely don't qualify if…
You'll visit the clinic four times over about four months. At your first visit, you'll be randomly assigned to receive either a stronger or weaker dose of the medication in patch form, which you'll wear for 30 minutes. You'll return at 2 months and 4 months for follow-up assessments, and if your pain is still significant at the 2-month visit, you may have the option to try the stronger dose. Throughout the study, you'll keep a simple daily log of your pain and any pain medications you take, and you'll have two brief blood draws to help researchers understand how the treatment affects inflammation in your body.
AI-generated summary from trial data · Jun 24, 2026 · Not medical advice
France