Plain-English translation of NCT06446609 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is looking at people who have developed liver injury as an unexpected side effect of a medication they were taking. The researchers want to understand why some patients experience severe itching along with their liver problems, and how long these symptoms persist after stopping the medication. By collecting detailed information from 50 patients, the team hopes to identify patterns that could help doctors predict and treat this condition better in the future.
Drug-induced liver injury is rare but serious, and it's one of the main reasons medications get pulled from the market. Right now, doctors don't have good ways to predict who will develop this problem or how long symptoms will last — especially the itching, which can significantly affect quality of life. This study aims to fill that gap by understanding the natural course of the condition and identifying which patients might benefit from new treatments being developed.
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As a participant, you would enroll in the study shortly after your diagnosis and share your medical records and information about your symptoms, including any itching you experience. The study will track your recovery over time to understand how long symptoms typically last and what factors influence your individual outcome. You'll be part of a research registry that helps doctors learn how to better identify and care for future patients with this condition.
AI-generated summary from trial data · Aug 14, 2026 · Not medical advice
United Kingdom
Sponsor
University of Nottingham
Collaborators
Ipsen, National Institute for Health Research, United Kingdom
Enrollment target
~50 participants
Started
June 2025
Primary completion
May 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in July 2026.
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Central contact
Elinor Study Coordinator
University of Nottingham
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