Plain-English translation of NCT06447428 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is a one-year study that watches how depression affects thinking and memory in people aged 60 and older. Researchers will give you simple thinking and memory tests at the start, and then again at 6 months and 12 months to see how your cognitive abilities change over time. The study aims to understand which older adults with depression are more likely to develop cognitive decline and what factors might predict these changes.
Many older adults with depression also experience problems with thinking and memory, but doctors don't fully understand how depression leads to these cognitive changes over time. This study exists to identify patterns and risk factors so that doctors can better predict who might develop more serious thinking problems and potentially help them sooner.
You will complete simple tests of thinking and memory at the beginning of the study, designed to take about 20–30 minutes. You'll then return at 6 months and again at 12 months to repeat these tests and answer questions about your mood, sleep, stress level, and social connections. The researchers are simply tracking how your cognitive abilities change naturally over the year—there is no new medication or special treatment involved in this study.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
China
Sponsor
Fujian Medical University
Enrollment target
~400 participants
Started
June 2023
Primary completion
August 2024
Age range
60 Years and older
Last updated on clinicaltrials.gov in June 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Hong Li
Fujian Medical University