Plain-English translation of NCT06448637 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Coronary Artery Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing two different ways to treat blocked coronary arteries—the vessels that supply blood to your heart. One approach uses a drug-coated balloon, and the other uses a drug-eluting stent (a tiny metal tube that stays in place). Researchers want to see which treatment better preserves your heart's natural ability to adjust blood flow 8 months after the procedure.
When coronary arteries become blocked, doctors need to open them up to restore blood flow. While stents have been used for many years, drug-coated balloons are a newer option that doesn't leave a permanent device in your artery. This study will help doctors understand which approach works better for larger arteries and which one keeps your heart functioning more naturally over time.
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You will be randomly assigned to receive either a drug-coated balloon or a drug-eluting stent to open your blocked artery. After the procedure, you will return for follow-up visits, including one at 8 months where doctors will use special imaging and testing—including injections of medications to measure how well your heart vessel functions—to compare how each treatment performs. The study involves about 94 patients across multiple medical centers.
AI-generated summary from trial data · Aug 18, 2026 · Not medical advice
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