Plain-English translation of NCT06448637 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Coronary Artery Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing two different approaches to treating blocked coronary arteries (the blood vessels that supply your heart). One approach uses a Drug Coated Balloon (DCB)—a special balloon coated with heart-protective medication that opens the artery without leaving anything permanently behind. The other uses a Drug Eluting Stent (DES)—a small mesh tube coated with medication that stays in place to keep the artery open. Researchers want to see which treatment helps your arteries function better over time.
Current treatments for blocked arteries work well, but doctors want to understand whether leaving a permanent stent in place is always necessary, or whether the temporary balloon approach might work just as well—especially in larger arteries. This study will help guide future treatment decisions.
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You will be randomly assigned to receive either the drug-coated balloon or the drug-eluting stent to treat your blocked artery. After the procedure, you will return for follow-up visits, with a major assessment at 8 months that includes special heart imaging and tests to measure how well your artery is functioning. The study involves multiple medical centers, and the entire follow-up period lasts approximately 8 months.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
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