Plain-English translation of NCT06449326 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a treatment called iTBS (intermittent theta-burst stimulation), which uses magnetic pulses to stimulate specific areas of the brain that may be overactive in people with post-traumatic stress disorder. Researchers will use brain imaging scans to create a personalized map of your brain and target the treatment to the area most likely to help you. Half of participants will receive active treatment and half will receive a sham (fake) treatment to see if the real treatment works better.
Post-traumatic stress disorder can be difficult to treat with medications and therapy alone, and many veterans struggle with persistent symptoms. This trial is testing whether using detailed brain imaging to customize where the treatment targets might make it more effective at reducing trauma-related symptoms.
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You will start with a baseline visit where you'll complete assessments, answer questions about your symptoms, and have brain imaging scans (fMRI and DTI). Then you'll receive 50 sessions of the treatment over two weeks (10 sessions per day, five days a week). After treatment ends, you'll repeat your initial assessments and brain scans, then have follow-up phone calls at one, three, and six months to track how you're doing and whether benefits last.
AI-generated summary from trial data · Jul 8, 2026 · Not medical advice
United States