Plain-English translation of NCT06450873 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This study is testing whether turkey tail mushroom extract (Trametes versicolor) can help slow the growth of a specific type of breast cancer before surgery. Researchers want to see if taking this natural supplement daily for 3–6 weeks before your scheduled surgery might affect how fast cancer cells are dividing. If the medication shows promise in this small pilot study, it could lead to larger trials in the future.
Some research suggests that compounds in turkey tail mushrooms may support the immune system and slow cancer growth, but this hasn't been thoroughly tested in breast cancer patients. This trial aims to see whether this treatment is worth studying further as a possible supportive therapy alongside standard surgery.
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You would take the turkey tail mushroom extract by mouth twice daily starting when you enroll in the study and continuing until the day before your scheduled breast surgery—a period of 3 to 6 weeks. A small piece of your tumor tissue would be checked before and potentially after the treatment to see if the medication affected cancer cell growth. You would also complete a brief daily diary about how you're feeling, including your mood and energy levels, and be asked about any side effects. After surgery, you'll have a follow-up visit 1–4 weeks later to make sure everything is going well.
AI-generated summary from trial data · Jul 9, 2026 · Not medical advice
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