Plain-English translation of NCT06451146 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is testing the safety and effectiveness of a device called orbital atherectomy, which rotates to help remove hardened calcium buildup in clogged heart arteries. The study will follow 500 patients who have moderate to severe calcium deposits in their coronary arteries and need a heart procedure called angioplasty. Doctors will use the orbital atherectomy device to help clear these blockages before placing a stent (a small metal tube) to keep the artery open.
When calcium hardens inside heart arteries, traditional angioplasty balloons and tools may not work as well. This trial exists to learn whether the orbital atherectomy device—which uses a rotating mechanism to break up calcium—can safely improve outcomes for patients with these challenging, heavily calcified blockages.
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If you enroll, your cardiologist will use the orbital atherectomy device during your scheduled angioplasty procedure to help clear the hardened calcium from your blocked artery. Your doctor will then place a stent to keep the artery open, and you will receive standard follow-up care. The trial collects information about whether the procedure was successful and whether you experience any complications, using this data to build a registry (a database) of patient outcomes.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
Poland
Sponsor
Regional Cardiology Center, The Copper Health Centre (MCZ),
Collaborators
Department of Cardiology, Provincial Specialized Hospital in Legnica, 59-200 Legnica, Poland.
Enrollment target
~500 participants
Started
May 2022
Primary completion
May 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in August 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Piotr Rola, MD; PhD
Regional Cardiology Center, The Copper Health Centre (MCZ),
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.