Plain-English translation of NCT06453720 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand whether the bacteria living in your gut can predict how well your Crohn's disease treatment will work. This study collects samples from your stool and intestines during a routine colonoscopy to analyze your gut bacteria. By identifying patterns in these bacteria, doctors hope to eventually personalize treatment choices and help patients find the right medication faster.
Crohn's disease affects everyone differently, and medications that work well for one person may not work for another. Right now, doctors have to try different treatments and wait to see what happens. This research aims to find a way to predict treatment success early by looking at each person's unique gut bacteria, so patients can avoid wasting time on treatments that won't help them.
You likely qualify if…
You likely don't qualify if…
You'll provide a stool sample the day before your regularly scheduled colonoscopy and bring it with you. During the colonoscopy (which you'd be having anyway), doctors will collect additional samples from your intestines and a mucosal washing. Two weeks after your scope, you'll collect another stool sample at home using a kit provided at your appointment. If you have active disease requiring new treatment, the study will follow you for 12 months to see how well the treatment works and compare those results to your bacterial patterns.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
Canada