Plain-English translation of NCT06456931 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research compares two different mindfulness-based programs to see if they help reduce lingering depression symptoms. One program uses traditional Buddhist teachings and meditation practices, while the other uses a secular mindfulness approach combined with cognitive therapy. Both programs involve 8 weeks of weekly sessions plus daily home practice, and researchers will follow participants for a full year to see which approach works better and whether either one prevents depression from returning.
Many people with depression continue to experience some depressive symptoms even after taking medication or receiving standard treatment. This trial exists to explore whether mindfulness-based programs—especially ones that incorporate spiritual or religious elements—might offer an additional way to help these people feel better and stay well long-term.
If you join this study, you will be randomly assigned to one of two groups. Over 8 weeks, you'll attend a weekly 2-hour session with about 14 other participants and practice meditation or mindfulness techniques at home for about 40 minutes daily. Depending on which group you're in, your sessions will focus either on traditional Buddhist meditation and teachings or on secular mindfulness combined with cognitive therapy techniques. After the 8-week program ends, researchers will check in with you at 6 months and 12 months to see how you're doing and whether your depression symptoms have returned.
AI-generated summary from trial data · Jun 26, 2026 · Not medical advice
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