Plain-English translation of NCT06457386 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether patients hospitalized with a Staphylococcus aureus blood infection (a serious bacterial infection) actually need a heart imaging test called an echocardiogram. The study will randomly assign 700 patients to either receive the standard heart imaging test or to skip it and only get the test if new warning signs appear. Researchers want to know if the test is truly necessary for patients at low risk of developing a heart valve infection.
Many patients with staph blood infections get a heart imaging test routinely, even though most of them won't develop a serious heart problem. This trial exists to see if doctors can safely avoid this test in low-risk patients, which would save time, reduce discomfort, and free up hospital resources for patients who really need the imaging.
You likely qualify if…
You likely don't qualify if…
If you join this trial, you'll be randomly assigned to one of two groups: either you'll receive a standard heart ultrasound (echocardiogram) within 14 days, or you'll skip the routine test and only get imaged if you develop new symptoms or warning signs. Either way, you'll receive standard antibiotics for your staph infection. The study team will follow up with you at 90 days after your diagnosis to check if the infection has returned or if any complications have developed.
AI-generated summary from trial data · Jun 16, 2026 · Not medical advice
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