Plain-English translation of NCT06461910 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether a combination of three medications—including , , and a chemotherapy regimen called SOX—can help shrink advanced stomach or gastroesophageal junction cancer before surgery. The goal is to give patients this medication combination before their operation to see if it helps eliminate cancer cells and improves their chances of a successful surgery with no remaining cancer.
Advanced stomach cancer is difficult to treat, and surgery alone may not remove all cancer cells. This trial is testing whether giving this medication combination before surgery can better prepare the body and improve the chances that surgeons can remove all the cancer.
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You would receive the three-medication combination over several weeks before undergoing surgery to remove your cancer. During treatment, you will have regular clinic visits for blood tests, imaging scans, and physical exams to monitor how the cancer is responding and watch for any side effects. After completing the medication phase, you will have surgery as planned, and then doctors will follow your health over time to see how well the treatment worked.
AI-generated summary from trial data · Jun 27, 2026 · Not medical advice
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