Plain-English translation of NCT06462196 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study collects detailed information from people being treated for depression, bipolar disorder, or suicidal thoughts at the National Institute of Mental Health. Researchers want to understand which treatments work best for which people, and they're looking for biological clues that could predict who will respond well to treatment. You would receive personalized, standard care tailored to your needs while researchers track your progress through ratings and some neurobiological tests.
Many people with depression and bipolar disorder don't respond well to standard treatments, and doctors don't yet have reliable ways to predict who will benefit from which approach. This research aims to find patterns and biological markers that could help match patients with the right treatment from the start.
You likely qualify if…
You likely don't qualify if…
You would receive personalized treatment for your condition at the National Institute of Mental Health, with the goal of getting you stable and then connecting you with ongoing care in your community. Throughout your treatment, you would complete depression and suicide risk rating scales both in person and remotely. At the beginning and end of the study, you would also undergo some neurobiological tests (such as blood work or brain imaging) to help researchers identify patterns that predict treatment success.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States