Plain-English translation of NCT06463392 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
After radiation therapy for nasopharyngeal cancer, some patients develop damage to skull-base bone — a severe complication that can be confused with cancer returning. This study is building an artificial intelligence tool using MRI scans and patient data to help doctors tell the difference between bone damage and actual cancer recurrence. The AI is being trained to be more accurate than radiologists reviewing scans alone.
Skull-base bone damage after radiation is often misdiagnosed as cancer returning, which leads to unnecessary treatment and delays in proper care. A better diagnostic tool could improve quality of life and prevent serious complications like blood vessel rupture.
You likely qualify if…
You likely don't qualify if…
You would visit the hospital for imaging scans (MRI of your nasopharynx and neck), blood tests (including tests for Epstein-Barr virus), and possibly a small tissue biopsy to confirm your diagnosis. The study is cross-sectional, meaning these visits would happen over a defined period rather than spanning months or years. Your scans and test results would then be used to train and test the artificial intelligence tool.
AI-generated summary from trial data · Jul 7, 2026 · Not medical advice
China
Sponsor
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Collaborators
Sun Yat-sen University, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China
Enrollment target
~312 participants
Started
July 2024
Primary completion
December 2029
Age range
18 Years and older
Last updated on clinicaltrials.gov in October 2024.
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Central contact
Xiang-Wei Kong, Ph.D.
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
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