Plain-English translation of NCT06469931 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Carpal tunnel syndrome happens when a nerve in your wrist gets squeezed, causing pain and weakness in your hand. This trial compares two treatments — ozone therapy and extracorporeal shock wave therapy (ESWT) — to see which one works better when added to standard care like hand exercises and a wrist splint. Both groups will also do the same exercises and wear a splint to support their wrist.
While exercises and splints help many people with carpal tunnel syndrome, doctors are looking for better ways to reduce pain and nerve damage. Ozone therapy is a newer option that researchers think might reduce inflammation and pain, but it hasn't been studied much for this condition. This trial will help doctors understand if it's as good as, or better than, shock wave therapy.
You will be assigned to one of two groups. Both groups will do range-of-motion exercises for your wrist and hand and wear a splint. One group will receive three sessions of ozone therapy over three weeks (once a week), while the other group will receive shock wave therapy once a week for three weeks. Doctors will use ultrasound to check your median nerve and test your grip strength before and after treatment to measure how well each treatment works.
AI-generated summary from trial data · Jun 16, 2026 · Not medical advice
Turkey (Türkiye)
Firat University
Enrollment target
~30 participants
Started
June 2024
Primary completion
August 2024
Age range
18 Years – 65 Years
Last updated on clinicaltrials.gov in June 2024.