Plain-English translation of NCT06470516 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Schizophrenia research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing high-frequency transcranial alternating current stimulation (Hi-tACS), a noninvasive brain stimulation technique, to see if it can improve cognitive problems like memory, attention, and thinking speed in people with schizophrenia. About 98% of people with schizophrenia experience decline in thinking abilities, and current medications often don't fully address this problem. This study is exploring whether this new brain stimulation approach could offer additional help.
Cognitive impairment—problems with memory, attention, and reasoning—is a core challenge in schizophrenia that doesn't respond well to standard medications. The new treatment being tested uses stronger, more widespread electrical stimulation than older brain stimulation techniques, and early research suggests it may be safer and more effective for improving thinking skills.
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If you enroll, you would receive brain stimulation sessions twice a day for 40 minutes each time, with at least 3 hours between sessions, for 30 consecutive days. You'll be randomly assigned to either receive active treatment or a sham (placebo) stimulation—neither you nor the researchers will initially know which. The treatment involves electrodes placed on your scalp delivering gentle electrical currents; it causes no pain or discomfort. You would need to commit to daily visits to the research center for the full month.
AI-generated summary from trial data · Jun 23, 2026 · Not medical advice
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