Plain-English translation of NCT06470958 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Migraine research guide →Researchers want to understand what happens in the brain during migraines that are linked to the menstrual cycle. This study will use MRI scans—a type of brain imaging that is safe and painless—to take daily pictures of your brain starting a few days before your period is expected and continuing through your migraine (or up to five days). By comparing brain scans from women with menstrual migraines to women without migraines, the study team hopes to uncover new information about how these headaches develop.
Migraines that happen around menstruation are unpredictable and hard to study in the lab. This research takes advantage of the predictable timing of the menstrual cycle to finally understand what changes in the brain right before and during these migraines—knowledge that could lead to better treatments in the future.
You would come to the Danish Headache Center for daily MRI brain scans starting 2–3 days before you expect your period to begin, and continue scanning through the day of your migraine headache or for up to five consecutive days. Each scan is painless and takes place in an MRI machine (a large tube that takes detailed pictures of your brain). You'll need to avoid coffee, tea, alcohol, and certain medications for 12 hours before each scan day, and stick with the same birth control method throughout the study.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
Denmark
Sponsor
Danish Headache Center
Enrollment target
~40 participants
Started
April 2024
Primary completion
January 2026
Age range
18 Years – 40 Years
Sex
Female only
Last updated on clinicaltrials.gov in November 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Faisal Mohammad Amin
Danish Headache Center