Plain-English translation of NCT06471738 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a new combination of three medications—, , and —for people with follicular lymphoma who have never been treated before. Currently, standard treatment often includes chemotherapy, which can cause serious side effects. The study is investigating whether this medication combination, without chemotherapy, can work just as well while causing fewer harmful effects.
Follicular lymphoma grows slowly but is usually incurable with current treatments, and about one in five patients relapse within two years. This medication combination aims to offer a gentler first-line treatment option that avoids the bone marrow damage, heart problems, and other serious side effects associated with traditional chemotherapy.
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You will take by mouth twice daily throughout the study and receive infusions every four weeks. In the first three cycles (about 12 weeks), you'll receive these two medications. After that, depending on how well you respond, the doctors may add to your treatment. The trial lasts approximately 9 cycles (about 36 weeks), with regular clinic visits to check your blood work and see how the cancer is responding.
AI-generated summary from trial data · Aug 5, 2026 · Not medical advice
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