Plain-English translation of NCT06472336 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Stroke research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
When someone has a stroke caused by a large blood clot in the brain, doctors typically try to remove it using a procedure called endovascular treatment. However, this doesn't always work—especially when the clot is caused by a condition called intracranial atherosclerosis (buildup of plaque inside brain arteries). This trial is testing whether placing a permanent stent (a tiny metal tube) in the blocked artery can help restore blood flow when standard removal attempts have failed.
When standard clot removal doesn't work, over 70% of patients end up with severe disability or death. Stents are already used successfully in heart attacks, but doctors aren't sure if they're safe and effective for brain strokes, partly because of concerns about bleeding. This trial will provide clear evidence about whether this treatment actually helps.
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You would be randomly assigned to one of two groups: one group would receive a stent placed in the blocked brain artery (with or without balloon dilation to help open it), while the other group would continue with standard clot removal attempts. The actual stent placement or additional treatment would happen during your emergency hospital care. You would then be followed up to track your recovery and any side effects, with the study team monitoring your outcomes over time to see which approach works better.
AI-generated summary from trial data · Aug 15, 2026 · Not medical advice
Switzerland