Plain-English translation of NCT06472557 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is a research study that will follow people with Spinocerebellar Ataxia Type 27B (a rare genetic condition affecting balance and coordination) and their family members over time to understand how the disease progresses. Researchers will collect medical information, perform movement tests using special sensors, and take blood and other biological samples from participants to build a detailed picture of the disease. The goal is to identify the best ways to measure changes in the disease so that future treatments can be tested more effectively.
Spinocerebellar Ataxia Type 27B is a very rare genetic disease, and doctors don't yet fully understand how it develops and changes over time. By carefully tracking a large group of affected people and their relatives—including those who may develop the disease in the future—researchers hope to find the most reliable measurements for detecting disease progression and testing new treatments.
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If you join this study, you will visit a research center once per year for assessments. During each visit, you'll have tests that measure how you walk and move your arms using special sensors, answer questions about your health and symptoms, and provide biological samples (blood, urine, and possibly cerebrospinal fluid or skin). All of your information will be entered into a secure research database. The study is happening at multiple centers internationally, so you may be able to participate at a location near you.
AI-generated summary from trial data · Oct 12, 2026 · Not medical advice
Czechia
Germany
Italy
Spain