Plain-English translation of NCT06473597 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Migraine research guide →Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing whether (Nurtec ODT) works as well as or better than Rizatriptan (Maxalt MLT-ODT) for treating acute migraine headaches in the emergency department. Both medications dissolve on your tongue and are designed to relieve migraine pain quickly. Researchers want to compare how well each one works and whether either is safer than the other.
Many migraine sufferers go to the emergency department for relief during a severe attack. While several medications exist to treat migraines, doctors want to know which ones work best and most safely when patients need urgent help, especially since this medication represents a newer approach to migraine treatment.
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You will be enrolled at the emergency department of Maimonides Medical Center. After the treating physician confirms you meet the study criteria, researchers will ask you to sign a consent form. You will then receive one of the two study medications as an orally disintegrating tablet. Researchers will measure your pain before taking the medication and at set times afterward to see how well the treatment works and to monitor for any side effects.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
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