Plain-English translation of NCT06474169 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand why people with end-stage kidney disease get serious infections more often and have weaker immune responses. This study will compare blood samples from three groups—people with advanced kidney disease, people with earlier-stage kidney disease, and healthy volunteers—to map out exactly how the immune system changes as kidney disease gets worse.
People with end-stage kidney disease face a much higher risk of life-threatening infections, which are the second leading cause of death in this population. Right now, doctors can't predict which patients will struggle most with infections. This research aims to fill that gap by identifying the specific immune system changes that make some kidney disease patients more vulnerable.
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Your participation is straightforward: you'll come in for a single visit where researchers will take one blood sample. The blood will be analyzed to study how your immune system is functioning. There are no ongoing visits or long-term follow-up required—it's a one-time commitment designed to be as simple as possible for you.
AI-generated summary from trial data · Jun 28, 2026 · Not medical advice
France
Sponsor
Centre Hospitalier Régional d'Orléans
Enrollment target
~100 participants
Started
November 2024
Primary completion
December 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in June 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Manon DEKEYSER, PhD
Centre Hospitalier Régional d'Orléans
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.