Testing a new cutting tool for removing precancerous throat growths

This trial is testing a novel bipolar radiofrequency ablation knife — a specialized cutting tool used during endoscopic submucosal dissection (a minimally invasive procedure to remove precancerous growths from your esophagus). The new tool uses lower energy than traditional cutting instruments, which may reduce complications like pain, infection, and scarring that patients sometimes experience after this type of procedure.

Currently, doctors use traditional cutting tools that generate a lot of heat, leading to post-procedure complications in up to 40% of patients — including pain, fever, and the need for blood thinners and antibiotics. Additionally, when large areas are treated, patients often develop strictures (narrowing of the esophagus) that require repeated stretching procedures. This new treatment is designed to accomplish the same removal goal with less tissue damage and fewer complications.