Plain-English translation of NCT06476808 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This is one of the first times this treatment has been tested in people.
This is a first-in-human study testing a new medication called to treat advanced cancers including high-grade serous ovarian cancer, uterine serous cancer, and non-small cell lung cancer. Researchers want to find the safest and most effective dose of this medication, and whether it actually helps shrink tumors. The trial will start with lower doses and gradually increase them as they learn more about how the medication works.
Many people with these advanced cancers have limited treatment options, and existing therapies don't work for everyone. This trial exists to see whether this new medication could offer hope to patients who need better options.
You likely qualify if…
You likely don't qualify if…
The trial has two parts: first, researchers will test increasing doses of the medication with small groups of participants to find a safe dose, then they'll expand to test that dose in more people. You'll need to provide a tissue biopsy (a small sample taken from your tumor) before starting treatment. You'll likely visit the clinic regularly to receive the medication, have blood tests, imaging scans, and be monitored for any side effects.
AI-generated summary from trial data · Jun 30, 2026 · Not medical advice
United States