Plain-English translation of NCT06477952 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This trial is testing whether , a medication derived from cannabis, can help reduce obstructive sleep apnea—a condition where people stop breathing repeatedly during sleep. Researchers want to understand whether this medication could work better and be easier to use than the machines (like CPAP devices) that are currently used to treat this condition. The study will help doctors figure out which patients might benefit most from this new treatment.
Sleep apnea affects millions of Americans and increases the risk of serious health problems like heart disease, stroke, and diabetes. Current treatments either involve wearing a mask machine every night (which many people find uncomfortable and stop using) or surgery (which isn't always successful). This study exists because researchers need to find new, easier medication options to help more people manage this serious condition.
You likely qualify if…
You likely don't qualify if…
If you qualify and enroll, you will take the study medication daily for two weeks. Before starting, you will have an overnight sleep study to measure your breathing. You will also have blood tests and answer questions about your health and mood. During the two-week treatment period, researchers will monitor you closely, and after finishing the medication, you'll have another sleep study to see if your breathing has improved.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States
Phase
Safety & dosing / Early efficacy
Sponsor
VA Office of Research and Development
Collaborators
University of Illinois at Chicago
Enrollment target
~120 participants
Started
August 2025
Primary completion
December 2026
Last updated on clinicaltrials.gov in September 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Bharati Prasad, MD
Jesse Brown VA Medical Center, Chicago, IL
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.