Blood test to detect hidden stomach cancer spread

Plain-English translation of NCT06478394 on ClinicalTrials.gov ↗ · Source last updated June 2024 · Translation generated June 2026 · How we translate trials

What is this trial?

This trial is testing a new way to find cancer cells that have spread to the lining of your abdomen (belly), using simple blood samples analyzed by artificial intelligence. Right now, doctors struggle to detect these hidden cancer cells with standard imaging or surgery. This study hopes that analyzing RNA patterns in your blood could catch these spread cells early, before they cause more problems.

Advanced stomach cancer often spreads to the abdominal lining in ways that are hard to see on standard scans or during surgery. Catching this spread earlier could help doctors choose better treatment options and improve survival.

Do you qualify?

You likely qualify if…

you have been diagnosed with locally advanced stomach cancer confirmed by imaging and tissue testing
you are 18 years old or older
you are able to provide informed consent to participate
your blood counts and organ function (liver, kidneys, bone marrow) are adequate based on lab tests
you are physically able to manage self-care, even if you cannot do strenuous work
you are willing to provide blood samples at multiple time points during the study

You likely don't qualify if…

you have cancer that has already spread to distant parts of your body beyond the abdominal lining
you have had another type of cancer in the past five years (except non-melanoma skin cancer or cervical cancer in situ)
you have serious heart disease, uncontrolled diabetes, severe infections, or other severe conditions that would make it unsafe to participate
you are pregnant or breastfeeding
you have a weakened immune system (such as HIV/AIDS) or are taking immunosuppressive medications

What participation looks like

You will visit the study center at several timepoints to have blood samples taken. Researchers will analyze the RNA in your blood using artificial intelligence to look for signs of hidden cancer spread. The study involves no medication or invasive procedures—just blood draws similar to routine lab work. You'll need to be willing to follow up with the study team and provide samples at the times they request throughout your cancer care.

AI-generated summary from trial data · Jun 7, 2026 · Not medical advice

Trial locations(1 site)

China

Department of General Surgery, Shijiazhuang, Hebei

View full record on ClinicalTrials.gov