Plain-English translation of NCT06482814 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Hypertension research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers want to understand how not getting enough sleep affects blood pressure, particularly in young adults whose parents have high blood pressure. You would stay in the hospital for two separate 10-day periods, during which researchers will monitor your sleep, blood pressure, and other health markers while you experience both normal sleep and restricted sleep conditions.
High blood pressure runs in families, and sleep problems are known to affect heart health. This study aims to learn whether people with a family history of high blood pressure are more vulnerable to blood pressure changes when they don't get enough sleep—information that could help identify who is at risk and lead to better prevention strategies.
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You would complete two separate 10-day inpatient hospital stays. During each stay, you'll have a 3-day baseline period to acclimate, followed by 5 days where your sleep is either restricted (shortened) or normal depending on which group you're in first, and then 2 days of recovery. Throughout your stays, the research team will monitor your blood pressure, collect blood samples, track your sleep, and measure various health markers. The second 10-day stay would repeat this process with the opposite sleep condition, so you experience both restricted and normal sleep during the study.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States
Sponsor
Mayo Clinic
Collaborators
National Heart, Lung, and Blood Institute (NHLBI)
Enrollment target
~44 participants
Started
February 2025
Primary completion
April 2029
Age range
18 Years – 35 Years
Last updated on clinicaltrials.gov in August 2025.
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Central contact
Sabah Munir
Mayo Clinic
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.