Plain-English translation of NCT06483061 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This research trial is testing whether a medication called can help doctors see the tiny blood vessels in a specific part of the brain called the hippocampus more clearly on MRI scans. The study involves people with temporal lobe epilepsy and healthy volunteers. Researchers believe this medication will create detailed images that could help predict which patients might benefit from surgery.
For people with temporal lobe epilepsy caused by a condition called hippocampal sclerosis, surgery can sometimes help—but doctors don't have a good way to predict who will benefit before operating. This treatment aims to create much more detailed images of the brain that could help doctors make better treatment decisions.
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You will receive an intravenous infusion (through an IV) of the contrast medication, which takes about 30 minutes to administer. After that, you will undergo an MRI scan so doctors can capture detailed images of blood vessels in your hippocampus. The entire visit will likely take a few hours. The study is currently recruiting participants, so you would be involved for the duration of the imaging visit.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
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