Plain-English translation of NCT06485336 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether atorvastatin, a medication commonly used to manage cholesterol, can help prevent chronic migraines. Researchers have seen promising results in smaller studies, and now want to confirm whether this medication works in a larger group of people. The goal is to see if the medication reduces how often migraines occur and whether it has a good safety profile.
Chronic migraine is a serious condition that affects quality of life and work productivity. Current preventive treatments don't work well for everyone, so researchers are looking for new options. Earlier studies suggested this medication might help, but larger research is needed to be sure it's truly effective.
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If you join this study, you will take either the medication or a placebo (a dummy pill) once daily for 84 days. You'll need to keep a daily headache diary to track your migraines before and during the study. You'll visit the research clinic for check-ins and evaluations, and researchers will monitor how the treatment affects your migraine frequency and any side effects. Half of the participants will randomly receive the active medication, and half will receive placebo, so neither you nor the researchers will know which you're taking during the study.
AI-generated summary from trial data · Aug 7, 2026 · Not medical advice
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