Plain-English translation of NCT06485336 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
Researchers want to find out if atorvastatin, a medication commonly used to manage cholesterol, can also help prevent chronic migraines. Smaller studies have suggested this medication might reduce how often migraines happen, and this larger trial will confirm whether that benefit holds true in a bigger group of patients. The study will also check whether the medication is safe and affordable as a migraine prevention option.
People with chronic migraines need more treatment options that work well and don't cause serious side effects. Previous small studies hinted that this medication might help, but researchers need to test it in a larger, more rigorous way to be sure it actually works before recommending it to patients.
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You will take a pill once daily for 12 weeks—either the study medication or a placebo (a pill with no active ingredient). You'll keep a detailed headache diary to track your migraines during this time. The study is 'triple blind,' meaning you, your doctor, and the research team won't know which pill you're taking until the study ends. You'll likely have a few visits to the clinic for check-ins and to make sure the treatment is safe.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
Norway