Plain-English translation of NCT06485778 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a new approach to radiation therapy for people who have had surgery for oral tongue squamous cell carcinoma. Instead of treating the entire surgical area, researchers will deliver radiation only to the lymph nodes in the neck, which may help reduce side effects like difficulty swallowing or dry mouth. The study will track whether this focused approach is safe and effective, and how it affects patients' quality of life.
Standard radiation therapy after tongue cancer surgery can cause uncomfortable side effects because it treats the entire surgical area, including sensitive parts of the mouth and throat. This trial is testing whether limiting treatment to just the lymph nodes can reduce these side effects while still preventing cancer from returning.
You likely qualify if…
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If you qualify, you will receive radiation therapy delivered over 30 treatment sessions (fractions) aimed at the lymph nodes in your neck, while the oral tongue surgical site is excluded from treatment. You will have regular doctor visits to monitor for side effects and will be asked to complete questionnaires about your quality of life throughout and after treatment. The study involves close follow-up to track both your physical recovery and any cancer recurrence.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
United States