Plain-English translation of NCT06489119 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Coronary Artery Disease research guide →The MOOP-CAD study is looking at how plaque (fatty buildup) develops in coronary arteries — the vessels that supply blood to your heart. Researchers will use advanced imaging called OCT (a special camera that looks inside arteries) combined with analysis of immune cells in your blood to understand what makes some plaques stable and others more likely to break apart and cause a heart attack.
Currently, doctors can see plaque buildup in arteries but can't easily predict which plaques will become dangerous. This study hopes to identify early warning signs by studying the immune system's role in plaque progression, which could eventually help prevent heart attacks in people at risk.
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You would undergo a cardiac catheterization procedure (where a thin tube is inserted into an artery to reach your heart) during which doctors will use OCT imaging to examine your plaques in detail. Blood samples will be collected at the time of your procedure to analyze your immune cells. The study is observational, meaning researchers are watching and collecting data rather than testing a new medication — your participation involves donating samples and allowing imaging during a procedure you may already need for your heart condition.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
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