Plain-English translation of NCT06489327 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing melatonin, a natural hormone your body makes, to see if it can help calm children's anxiety before surgery. Researchers want to find out if melatonin works well for this purpose and whether a lower or higher dose works best. The study will compare two different amounts of the medication against a placebo (a dummy pill with no active ingredient).
Many children feel very scared and anxious before surgery—sometimes up to 8 out of 10 kids feel this way. Currently, doctors often use a strong medication called midazolam to calm children, but it can have unwanted side effects like confusion or over-sedation. This trial explores whether this natural, gentler medication might be a safer option.
You likely qualify if…
You likely don't qualify if…
Your child would receive one dose of either the medication or a placebo by mouth before surgery as part of their normal pre-surgery preparation. You and the medical team wouldn't know which group your child is in—that's kept secret to make sure the results are fair. The main thing you'd notice is whether the medication helps your child feel calmer and less anxious leading up to the surgery.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
Egypt
Iraq
Sponsor
Al-Azhar University
Collaborators
Al-Ayen Iraqi University
Enrollment target
~120 participants
Started
July 2026
Primary completion
December 2026
Age range
4 Years – 10 Years
Last updated on clinicaltrials.gov in January 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Neveen Kohaf, Ph.D
Al-Azhar University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.