Plain-English translation of NCT06492720 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This pilot study is testing a treatment called the NaviFUS System, which uses focused ultrasound waves directed into the brain to reduce seizure activity in people with drug-resistant epilepsy. The NaviFUS System delivers very brief, controlled ultrasound pulses to the specific area of the brain where seizures start. Researchers want to see if this treatment is safe and whether it can help decrease how often seizures occur.
Many people with epilepsy continue to have seizures even after trying three or more anti-seizure medications. This new treatment offers a potential option for patients who haven't benefited from standard drugs, using technology that may be able to calm the overactive brain cells causing seizures.
You likely qualify if…
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You would first complete an 8-week baseline period where you keep a detailed diary of your seizures. Then you'll be randomly assigned to receive either a lower or higher dose of the ultrasound treatment, which involves three 5-minute or three 10-minute sessions delivered twice in one week. After treatment, you'll continue tracking seizures and return for follow-up visits over the next 24 weeks, and you can keep taking your regular anti-seizure medications throughout the entire study.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
Taiwan
Sponsor
NaviFUS Corporation
Enrollment target
~16 participants
Started
September 2024
Primary completion
December 2026
Age range
18 Years – 65 Years
Last updated on clinicaltrials.gov in April 2026.
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Central contact
Sheang-Tze Fung, Ph.D.
NaviFUS Corporation
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.