Plain-English translation of NCT06494124 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Schizophrenia research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study compares two types of non-invasive brain stimulation — alternating current stimulation and direct current stimulation — to see if either can help reduce schizophrenia symptoms like hallucinations and improve thinking abilities. About 90 people with chronic schizophrenia will be divided into three groups: some will receive one type of stimulation, some will receive the other type, and some will receive a placebo (sham) treatment that feels real but doesn't actually work. Researchers will measure changes in symptoms and thinking skills over the 10-day treatment period.
Schizophrenia can be difficult to treat with medication alone, and many people continue to struggle with persistent symptoms like hearing voices. This trial explores whether targeted electrical stimulation of specific brain areas could offer a safe additional treatment option to help reduce these symptoms and improve quality of life.
You would visit the research center twice a day for 10 consecutive days to receive 20-minute brain stimulation sessions. Before treatment starts, during the middle (day 5), and after the final session, you'll complete questionnaires and thinking tests to measure any changes in your symptoms and cognitive abilities. The stimulation itself is non-invasive — electrodes are placed on your scalp, and you may feel mild tingling sensations, but the procedure is painless.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
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