Plain-English translation of NCT06494826 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Crohn Disease research guide →Researchers are trying to understand what happens in the gut of people with Crohn's disease by studying the bacteria and proteins present there. This study compares people who may have new-onset Crohn's disease with healthy people to see what differences exist. By analyzing stool samples and tissue collected during a colonoscopy, the researchers hope to decode how gut bacteria and intestinal proteins influence Crohn's disease.
Crohn's disease is a serious inflammatory bowel condition, but we still don't fully understand why it develops or how gut bacteria and the body's own proteins play a role. This research could help doctors detect and treat Crohn's disease earlier and more effectively.
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You will have two visits. At your first visit, you'll complete questionnaires about your medical history, diet, and lifestyle, then receive a stool collection kit to use at home before your colonoscopy. On your second visit (colonoscopy day), a gastroenterologist will assess your symptoms and collect stool samples, brush samples, and small tissue samples from different parts of your lower intestine during the procedure. The entire process takes place over about one to two weeks.
AI-generated summary from trial data · Jun 17, 2026 · Not medical advice
Israel