Plain-English translation of NCT06495658 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Crohn Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether prebiotics — plant-based supplements that feed beneficial gut bacteria — can improve the health of your gut and reduce inflammation in ulcerative colitis. Researchers believe that what you eat directly affects which bacteria live in your gut, and changing those bacteria might help control your symptoms. This study will track how your gut bacteria change over 16 weeks and whether the medication helps.
Ulcerative colitis happens when your gut becomes inflamed, but doctors still don't fully understand why. Recent research suggests that diet — especially foods with plants — can change your gut bacteria in ways that might reduce inflammation, so this study is testing whether adding this treatment can help.
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You would participate for 16 weeks total. Half of participants will start taking the prebiotic supplement immediately for 8 weeks, while the other half will wait 8 weeks before starting — this helps researchers understand whether the supplement itself is responsible for any changes. You'll provide stool samples at the beginning and after 8 weeks, and answer questions about what you eat. You should stop any other supplements you're taking during the study so the results are clear.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
United States