Plain-English translation of NCT06500260 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is a research study that follows children and young adults (ages 6–21) who have a CNKSR2 gene mutation. Researchers will collect information about how their seizures, speech, learning, and behavior change over time. The goal is to create a detailed picture of this rare condition so that future clinical trials testing new treatments will have good information to compare against.
Right now, very little is known about how CNKSR2-related conditions progress in children. By gathering detailed information from patients with this mutation, researchers can understand the natural course of the disease and use that knowledge to test new precision medicine treatments that might reduce seizures and improve development.
You and your child would visit the research clinic periodically so the team can collect medical information, review seizure records, and assess your child's development and behavior over time. The study is observational, meaning researchers are watching and documenting how your child's condition naturally progresses—there is no new medication being given as part of this study. The information gathered will help future researchers test new treatments.
AI-generated summary from trial data · Aug 2, 2026 · Not medical advice
United States
Sponsor
University of California, San Francisco
Enrollment target
~20 participants
Started
January 2022
Primary completion
April 2028
Age range
6 Years – 21 Years
Last updated on clinicaltrials.gov in July 2026.