Plain-English translation of NCT06500403 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is looking for better ways to diagnose porto-sinusoidal vascular disease (PSVD), a liver condition that can develop after certain chemotherapy treatments. Right now, doctors typically need to do a liver biopsy — a procedure where they take a tiny sample of liver tissue — to diagnose this condition. This study is testing whether specialized ultrasound scans that measure liver and spleen stiffness can do the job just as well, without needing an invasive procedure.
Some patients who receive platinum-based chemotherapy develop changes in their liver blood vessels that lead to serious complications. Currently, the only reliable way to diagnose this condition is through a liver biopsy, which is uncomfortable and carries small risks. This study aims to find non-invasive alternatives so patients can be diagnosed more easily and safely.
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As a participant, you would visit the hospital for specialized ultrasound scans that measure how stiff your liver and spleen are — these are painless, non-invasive tests similar to a regular ultrasound. The researchers will also review your medical history and chemotherapy records. The study is observational, meaning you won't receive any new medication; instead, you'll help doctors develop better diagnostic tools by allowing them to study how well these scans work.
AI-generated summary from trial data · Jun 27, 2026 · Not medical advice
China
Sponsor
Nanfang Hospital, Southern Medical University
Enrollment target
~1,000 participants
Started
February 2024
Primary completion
December 2028
Age range
18 Years – 80 Years
Last updated on clinicaltrials.gov in July 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Xiaofeng Zhang
Nanfang Hospital, Southern Medical University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.