Plain-English translation of NCT06500455 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing two different ways of delivering radiation therapy to treat cancer that has spread to the brain. One approach uses a single radiation session, while the other uses three sessions spread over time. The study will compare how well each approach controls the cancer and what side effects patients experience.
When cancer spreads to the brain, radiation therapy is a common treatment, but doctors aren't sure whether one large dose or multiple smaller doses works better. This trial will help answer that question so patients and doctors can make the best treatment choice.
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If you join this study, you'll be randomly assigned to receive either one radiation treatment session or three sessions (each lasting 30–90 minutes). You'll have imaging scans (CT and MRI) as part of your treatment planning. After your radiation therapy, you'll return for follow-up visits every 3 months for the first year, then every 4 months for another year, and finally every 6 months for 3 years to monitor how well the treatment is working and check for any side effects.
AI-generated summary from trial data · Jun 27, 2026 · Not medical advice
United States