Plain-English translation of NCT06503744 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing two different ways to treat early-stage lung cancer using radiofrequency ablation—a technique that uses heat to destroy cancer tumors. One approach accesses the tumor through the skin and chest (guided by CT scans), while the other uses a camera-guided tube passed through the airways to reach the tumor. The study will compare how well each method works and how safe they are.
Radiofrequency ablation is a well-established treatment for lung cancer, but doctors want to know if the newer approach through the airways (transbronchial) is just as effective and safe as the traditional approach through the chest wall (transthoracic). A rigorous comparison could give patients more treatment options and potentially less discomfort.
You likely qualify if…
You likely don't qualify if…
You will be randomly assigned to receive one of the two ablation techniques. The procedure itself typically takes a few hours, though the specific experience depends on which group you're in—one involves a needle guided by CT imaging, the other uses a bronchoscope passed through your airways. After your procedure, you'll have follow-up visits at 6 months, 1 year, and up to 3 years to check whether the tumor has been completely destroyed and to monitor for any side effects.
AI-generated summary from trial data · Jun 12, 2026 · Not medical advice
China
Sponsor
Shanghai Chest Hospital
Collaborators
Sir Run Run Shaw Hospital, Beijing Chao Yang Hospital
Enrollment target
~110 participants
Started
January 2024
Primary completion
December 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in April 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Jiayuan Sun, PhD
Shanghai Chest Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.