Exercise to reduce liver and muscle fat in metabolic liver disease

This trial is testing whether exercise—specifically different intensities of physical activity—can help improve fatty liver disease by reducing fat in both your liver and skeletal muscles. Researchers will compare three approaches: gentle stretching and meditation, moderate-intensity interval training, and high-intensity interval training. The goal is to understand which type of exercise works best and how it helps your body.

Many people with metabolic dysfunction-associated steatotic liver disease also have excess fat stored in their muscles, which may worsen liver disease. This trial exists to find out whether targeted exercise can improve both conditions and to understand the biological mechanisms behind how exercise helps.