Plain-English translation of NCT06507046 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a newer surgical approach called personalized alignment performs as well as the traditional mechanical alignment method for knee replacement surgery. Both approaches use robotic assistance to guide the surgical cuts with high precision. The study will compare how well each method works in terms of how your knee functions, how you feel after surgery, and how stable the new knee joint remains over time.
For decades, knee replacement surgery has used one standard alignment for all patients—regardless of how their knee naturally looked before arthritis developed. Some surgeons believe restoring each patient's original knee anatomy (personalized alignment) may lead to better results, but this approach hasn't been thoroughly tested with robotic surgery, and there are questions about whether it could cause the implant to shift over time.
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You would undergo knee replacement surgery using robotic assistance at Kristiansund Hospital, with your surgeon randomly assigned to use either the traditional mechanical alignment or the newer personalized alignment technique. After surgery, you would participate in follow-up visits and assessments to measure your knee function, strength, range of motion, and how you feel—along with imaging studies to track how well the implant stays in place over time. The trial involves 152 patients total, and you would be one of them.
AI-generated summary from trial data · Jun 15, 2026 · Not medical advice
Norway