Recruiting

Berry supplement to prevent thinking and memory problems in older adults

Plain-English translation of NCT06507254 on ClinicalTrials.gov ↗ · Source last updated June 2026 · Translation generated June 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This trial is testing whether Juice Plus Essentials Berry Blend Capsules can help protect your brain and keep your memory sharp as you age. Researchers believe that compounds found naturally in berries may work through your gut bacteria to protect brain health and lower the risk of Alzheimer's disease. Half of the participants will receive the medication, and half will receive a placebo (inactive pill) to see if there's a real difference.

There are no proven ways to prevent memory loss and Alzheimer's disease yet. This study exists because early research suggests that diets rich in berries and similar foods might protect the brain, possibly by changing how our gut bacteria work and how our brains function.

Do you qualify?

You likely qualify if…

you are 50 years of age or older
you have a parent, sibling, or child who was diagnosed with Alzheimer's disease
you typically eat a Western diet (high in meat, processed foods, and refined carbohydrates) rather than a very healthy diet
you are able to communicate well in English
you do not have memory or thinking problems at the start of the study

You likely don't qualify if…

you follow a vegetarian or vegan diet
you have already been diagnosed with dementia or are being treated for memory loss
you have used antibiotics in the past 3 months or probiotics in the past month
you have an allergy to berries or are unable to safely have an MRI scan
you are pregnant, nursing, or weigh more than 400 pounds

What participation looks like

You will take a daily capsule (either the medication or a placebo) for one year. During the study, you'll have visits where researchers will test your memory and thinking skills, take blood samples, collect stool samples to study your gut bacteria, and perform brain imaging scans using an MRI machine. The study takes place at multiple centers across the United States, with a validation group also participating in Northern Ireland.

AI-generated summary from trial data · Jun 16, 2026 · Not medical advice

Trial locations(1 site)

United States

University of California, Los Angeles, Los Angeles, California

View full record on ClinicalTrials.gov