Plain-English translation of NCT06508567 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing salvage MR-guided high-dose-rate brachytherapy — a type of internal radiation therapy — for men whose prostate cancer has come back in the prostate bed area after they previously received external radiation therapy. The study uses advanced imaging (MRI scans and PET scans) to precisely target the recurrent cancer with two focused doses of radiation delivered over 1-3 weeks. The goal is to treat the cancer effectively while minimizing side effects.
When prostate cancer returns after initial radiation therapy, treatment options are limited and challenging. This trial exists to test whether this newer, more precisely targeted approach can effectively treat the recurrence with better safety and quality of life compared to current standard options.
You likely qualify if…
You likely don't qualify if…
If you join this trial, you will start with baseline tests including quality of life questionnaires, PSA blood work, and an MRI scan for planning purposes. You will then receive two focused radiation treatments (called brachytherapy) spaced 7-21 days apart, each delivering a precise dose of radiation to the recurrent cancer area. After treatment, you will return for follow-up visits over the next 5 years, including PSA blood tests, imaging scans, and assessments of any side effects.
AI-generated summary from trial data · Jun 12, 2026 · Not medical advice
Canada
Sponsor
University Health Network, Toronto
Enrollment target
~20 participants
Started
August 2024
Primary completion
August 2026
Age range
18 Years and older
Sex
Male only
Last updated on clinicaltrials.gov in May 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Peter Chung, MD
University Health Network, Toronto
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.