Plain-English translation of NCT06509503 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Migraine research guide →Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
Researchers want to understand how birth control pills affect migraines in women and whether combining propranolol and ibuprofen can help reduce migraine frequency. This trial will compare women who use hormonal birth control with those who use non-hormonal contraception, tracking how often migraines occur and how severe they are over three months. The study aims to help doctors make better recommendations about migraine treatment for women using different types of contraception.
Migraines are common in women of reproductive age, and hormonal changes from birth control pills can affect how often and how severely migraines happen. Doctors need better information about which migraine treatments work best for women taking different types of contraception.
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You would be assigned to one of two groups based on your current contraception method. Throughout the three-month study, you would take propranolol daily to help prevent migraines and use ibuprofen when migraines occur. You would visit the clinic for a detailed health assessment at the start, complete questionnaires about your migraines and symptoms, and have regular follow-up appointments so researchers can track how the treatment is working and check for any side effects.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
Egypt
Phase
Post-approval monitoring
Sponsor
Kafrelsheikh University
Enrollment target
~400 participants
Started
July 2024
Primary completion
May 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 55 Years
Sex
Female only
Last updated on clinicaltrials.gov in October 2024.
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Central contact
mohamed G. Zeinhom, MD
Kafrelsheikh University
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