Plain-English translation of NCT06511063 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
Researchers at Mount Sinai are investigating whether two medications—Truvada and —that were originally developed to treat HIV might help reduce long COVID symptoms. Some people with long COVID have evidence of viral reactivation in their bodies, and this trial will test whether these medications can help. You would take one of these treatments (or a placebo) daily for 3 months to see if your symptoms improve.
Long COVID affects millions of people with ongoing fatigue, brain fog, breathing problems, and other symptoms that can last months or years after COVID infection. There are currently no proven treatments, so researchers are testing whether this medication—which targets viral activity in the body—might help reduce symptom burden.
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You would visit the research clinic for a baseline evaluation, then take your assigned medication (or placebo) by mouth once or twice daily for 90 days, depending on which group you're in. During this time, you'll complete surveys about your symptoms, have some laboratory tests, and track how you're feeling. The study team will check in with you regularly to monitor your progress and any side effects.
AI-generated summary from trial data · Jul 11, 2026 · Not medical advice
United States