Plain-English translation of NCT06512064 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Asthma research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research study is testing a smartphone-based approach called AWARE (Acoustic Waveform Respiratory Evaluation) that uses your phone's microphone and artificial intelligence to evaluate your lung health by analyzing the sounds your lungs make when you breathe. The researchers want to see if this technology can accurately diagnose different lung diseases like asthma, COPD, and cystic fibrosis, estimate how well your lungs are working, and detect when your condition is getting worse. If it works, this could help people monitor their lung health from home instead of only at specialty clinics.
Currently, doctors rely mostly on what patients tell them about their symptoms and only do objective lung function tests a few times a year at hospitals or clinics. This study exists because researchers believe a smartphone tool could let people check their lung health more often and objectively from home, which could help catch problems earlier and improve how well these diseases are controlled.
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You will visit the research center where you'll use a smartphone app to record your breathing sounds, then complete standard breathing tests (spirometry and oscillometry) that measure how well your lungs work. If you have a lung disease like asthma or COPD, you may be asked to return during a time when your symptoms get worse so researchers can see how the breathing sounds change. The study involves only non-invasive tests—no medications, injections, or surgeries.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
United States
Sponsor
Indiana University
Collaborators
National Heart, Lung, and Blood Institute (NHLBI), University of Pittsburgh
Enrollment target
~800 participants
Started
July 2024
Primary completion
April 2029
Age range
8 Years – 70 Years
Last updated on clinicaltrials.gov in October 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Elizabeth Rizzi, RN
Indiana University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.