Two knee pain treatments: trying them together versus one alone

This trial is testing whether doing two procedures in sequence works better for chronic knee pain than doing just one. One group will receive genicular nerve ablation (a procedure that reduces pain signals from the knee) followed one month later by geniculate artery embolization (a procedure that reduces blood flow to inflamed tissue in the knee). The other group will receive only the second procedure. Researchers want to see which approach gives people better pain relief and improves knee function.

Many people with chronic knee pain from arthritis don't get enough relief from standard treatments like physical therapy or injections. Doctors have two newer minimally invasive procedures available, but it's not yet clear whether doing them together in a specific order works better than doing just one, or which approach is safest.