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This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers are testing whether changing the stimulation pattern in an existing deep brain stimulation device — specifically using a slower frequency called theta stimulation — can improve memory and cognitive function in people with Parkinson's disease. This study involves adjusting settings in your existing device to target a specific brain region involved in thinking and memory. The goal is to see if this targeted approach works better than standard stimulation patterns.
Many people with Parkinson's disease experience problems with memory and thinking as their condition progresses. Researchers believe that by changing how the existing brain stimulation device works — targeting specific brain networks rather than using a one-size-fits-all approach — they may be able to help improve these cognitive symptoms.
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You will visit the research clinic where your deep brain stimulation device will be programmed with different settings on separate visits. You'll be blinded, meaning you won't know which setting is being tested at any given time — this helps ensure fair results. During each visit, you'll complete memory and thinking tasks while the device is set to different stimulation patterns, including no stimulation, theta stimulation targeting memory circuits, theta stimulation targeting movement circuits, and higher-frequency stimulation as a comparison.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
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