New cholesterol medication vs. standard therapy for early heart disease

This trial is testing whether a newer cholesterol medication called PCSK9 inhibitors, when combined with a standard statin, works better than taking a higher dose of statin alone for people with early-onset heart disease. Researchers will use special imaging (called optical coherence tomography) to look at the plaques in your heart arteries before and after one year of treatment to see how well each approach reduces blockages.

Young people with heart disease often have very high cholesterol that is hard to control with statin therapy alone. This medication may help lower cholesterol even more, potentially stopping plaques from growing or helping them shrink—but researchers need to confirm this works better than using higher statin doses.