Plain-English translation of NCT06521476 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether a medication called can help improve a breathing problem that happens during sleep in people taking medications for opioid use disorder. Sleep apnea from these opioid medications causes your breathing to stop and start throughout the night, which can lead to poor sleep quality, anxiety, and difficulty thinking clearly. The study will see if this medication can reduce those breathing interruptions and improve your overall wellbeing.
Medications that help treat opioid addiction can sometimes cause a type of sleep apnea where your breathing stops during sleep, but doctors don't fully understand how this affects patients long-term or what treatments work best. This trial exists to find out whether this medication can safely fix the breathing problem and improve sleep quality, mood, and cravings in people dealing with this specific situation.
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You will have an overnight visit at the research center where doctors will measure your sleep and breathing while you sleep, and test your anxiety, thinking ability, and cravings. After that first visit, you will be randomly assigned to take either the medication or a placebo pill (a dummy pill) every evening for 7 days. Finally, you will return for another overnight visit so the doctors can see whether the treatment helped improve your sleep and overall wellbeing.
AI-generated summary from trial data · Jul 3, 2026 · Not medical advice
United States